Pharmacology & ToxicologybioRxiv
In vitro effects of S-Licarbazepine as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders
E. Bayraktar, Y. Liu, U. B. S. Hedrich…·S. Lauxmann
This paper investigates the effects of S-Licarbazepine on SCN8A variants in neuroblastoma cells, showing variant-specific modulation of NaV1.6 channel biophysical properties.
DOI 10.1111/bph.15981