Ataxin-2 is essential for neurodevelopment in Drosophila and is a major regulator of the cytoskeleton.
U. del Castillo, R. Norkett, W. Lu, A. Serpinskaya, V. I. Gelfand
This study shows Ataxin-2 is essential for neurodevelopment in Drosophila by regulating cytoskeletal dynamics and organelle trafficking, leading to neurological defects and lethality.
bioRxiv · Jan 7, 2021Cell Biology