Author

V. I. Gelfand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 7 Biophysics· 1

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Research Focus:cell signaling & trafficking· 8 Organism:Drosophila· 7 Approach:experimental assay· 7 Research Focus:development & morphogenesis· 5 Research Focus:cell type annotation· 3 Assay:imaging· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

W. Lu· 6 shared M. Lakonishok· 4 shared U. del Castillo· 3 shared R. Norkett· 2 shared A. Rich· 1 shared A. S. Serpinskaya· 1 shared A. Serpinskaya· 1 shared B. Renganathan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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6 shared papersCell Biology

W. Lu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Self-organized intracellular twisters

S. Dutta, R. Farhadifar, W. Lu, G. kabacaoglu, R. Blackwell, D. B. Stein, M. Lakonishok, V. I. Gelfand, S. Shvartsman, M. Shelley

The paper studies fluid flows in Drosophila oocytes, showing the emergence of cell-spanning vortices through hydrodynamic interactions of microtubules and molecular motors.

bioRxiv · Apr 4, 2023Biophysics

Drosophila oocyte specification is maintained by the dynamic duo of microtubule polymerase Mini spindles/XMAP215 and dynein

W. Lu, M. Lakonishok, V. I. Gelfand

This study identifies Msps and dynein as a positive feedback loop that enhances dynein-dependent transport and determines oocyte fate in Drosophila.

bioRxiv · Mar 9, 2023 · PreprintCell Biology

Gigaxonin is required for intermediate filament transport

B. Renganathan, J. P. Zewe, Y. Cheng, M. Kittisopikul, P. Opal, K. M. Ridge, V. I. Gelfand

This study shows that gigaxonin is essential for intermediate filament transport by kinesin-1, and its loss leads to IF accumulation due to increased soluble vimentin oligomers.

bioRxiv · Aug 19, 2022Cell Biology

A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary

W. Lu, M. Lakonishok, A. S. Serpinskaya, V. I. Gelfand

The paper shows cortical dynein in Drosophila nurse cells moves microtubules to transport cytoplasm to the oocyte, revealing a novel mechanism for bulk cytoplasmic transport.

bioRxiv · Nov 12, 2021Cell Biology

Ataxin-2 is essential for neurodevelopment in Drosophila and is a major regulator of the cytoskeleton.

U. del Castillo, R. Norkett, W. Lu, A. Serpinskaya, V. I. Gelfand

This study shows Ataxin-2 is essential for neurodevelopment in Drosophila by regulating cytoskeletal dynamics and organelle trafficking, leading to neurological defects and lethality.

bioRxiv · Jan 7, 2021Cell Biology

Kinetochore protein Spindly controls microtubule polarity in Drosophila axons

U. del Castillo, H.-A. J. Muller, V. I. Gelfand

This study identifies Spindly as a protein that recruits dynein to the actin cortex in Drosophila axons, maintaining microtubule polarity and axonal structure.

bioRxiv · Mar 20, 2020Cell Biology

Competition between kinesin-1 and myosin-V define Drosophila posterior determination

W. Lu, M. Lakonishok, R. Liu, N. Billington, A. Rich, M. Glotzer, J. R. Sellers, V. I. Gelfand

This study shows that competition between kinesin-1 and myosin-V, influenced by cortical microtubule density, determines posterior localization of osk mRNA in Drosophila oocytes.

bioRxiv · Dec 5, 2019Cell Biology

Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding

V. I. Gelfand, R. Norkett, U. del Castillo, W. Lu

The paper identifies Trc as a kinase that regulates neurite outgrowth by modulating Pavarotti's interaction with microtubules through phosphorylation.

bioRxiv · Sep 24, 2019Cell Biology