U. Klümper

Tradeoffs of increasing temperatures for the spread of antimicrobial resistance in river biofilms

This study shows that higher temperatures increase natural ARG abundance in river biofilms but accelerate the loss of invading wastewater-born ARGs.

Cigarette smoking promotes the spread of antimicrobial resistance in the human lung and the environment

This study shows cigarette smoke increases antimicrobial resistance transfer between bacteria in lung and environmental settings.

Microbiome diversity: A barrier to the environmental spread of antimicrobial resistance?

The paper investigates whether microbial diversity acts as a barrier to the spread of antimicrobial resistance genes in the environment, finding that higher diversity correlates with lower ARG abundance in structured soils but not in dynamic rivers.

Exposure to environmental stress decreases the resistance of river microbial communities towards invasion by antimicrobial resistant bacteria

This study investigates how environmental stress affects the invasion of antimicrobial resistant bacteria into river microbial communities, finding that stress enhances invasion success by reducing community diversity.

Quantification of the mobility potential of antibiotic resistance genes through multiplexed ddPCR linkage analysis

This paper develops a sequencing-independent method to quantify the linkage between antibiotic resistance genes and mobile genetic elements using ddPCR, demonstrating its accuracy and applicability in environmental samples.

Microbiome and resistome dynamics along a sewage-effluent-reservoir continuum underline the role of natural attenuation in effluent receiving reservoirs

This study tracks microbiome and resistome changes along a sewage-effluent-reservoir system, showing that ecological interactions in reservoirs reduce antibiotic resistance more than physical processes in treatment reactors.

Interspecific competition can drive the loss of conjugative plasmids from a focal species in a microbial community

The paper shows that interspecific competition can reduce plasmid maintenance in microbial communities by increasing plasmid costs and accelerating plasmid loss from focal species.

Zinc can counteract selection for ciprofloxacin resistance

The paper shows that zinc cations increase the minimal selective concentration for ciprofloxacin resistance in E. coli by up to 5-fold.

Selection for antibiotic resistance is reduced when embedded in a natural microbial community

This study shows that antibiotic resistance selection is significantly reduced in natural microbial communities compared to single-species cultures.