Author

Uncaar Boora

University of Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Eline HendrixiD· 2 shared Mathew L. ColemaniD· 2 shared Sally C. FletcheriD· 2 shared Aida Maria Bertoli‐AvellaiD· 1 shared Almundher A. Al-MaawaliiD· 1 shared Alvin Yu Jin NgiD· 1 shared Arashpreet Kaur· 1 shared Breana ChamiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Eline HendrixORCID

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2 papers

Recent·Most cited

Inactivation of a protein hydroxylase complex impairs replication fork restart in cancer and neurodevelopmental disorders

Tristan J. Kennedy, Sally C. Fletcher, Uncaar Boora, Erin Fraser-Williams, Arashpreet Kaur, Gareth W. Hughes, Eline Hendrix, Joanna R. Morris, Stephen J. Smerdon, Mathew L. Coleman

This study investigates how JMJD5 mutations affect replication fork restart and genome stability in cancer and neurodevelopmental disorders.

bioRxiv · Nov 22, 2025 · PreprintCancer Biology

Inactivation of DRG1, encoding a translation factor GTPase, causes a Recessive Neurodevelopmental Disorder

Christian A. E. Westrip, Franziska Paul, Fathiya M. Al-Murshedi, Hashim Qaitoon, Breana Cham, Sally C. Fletcher, Eline Hendrix, Uncaar Boora, Alvin Yu Jin Ng, Carine Bonnard, Maryam Najafi, Salem Alawbathani, Imelda Lambert, Gabriel Padraigh Fox, Byrappa Venkatesh, , Mathew L. Coleman

This study identifies rare DRG1 variants causing a recessive neurodevelopmental disorder and shows their functional impact on GTPase activity and protein stability.

Genetics in Medicine · May 11, 2023Peer-reviewedGenetic & Genomic Medicine