Fluoxetine treatment during postnatal and juvenile temporal epochs evokes diametrically opposing changes in anxio-depressive behaviors, gene expression, mitochondrial function, and neuronal architecture in the medial prefrontal cortex
Utkarsha Ghai, Parul Chachra, Sashaina E. Fanibunda, Suchith Mendon, Amogh Bhaskaran, Ambalika Sarkar, Kowshik Kukkemane, Vivek Kumar Singh, Vidita A. Vaidya
This study shows that fluoxetine treatment during postnatal or juvenile periods leads to opposing effects on anxiety-depressive behaviors, gene expression, mitochondrial function, and neuronal structure in adult rats.
bioRxiv · Dec 29, 2023 · PreprintNeuroscience