Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF
Gian Luca Marongiu, Uwe Fink, Felix Schöpf, Andreas Oder, Jens Peter von Kries, Daniel Roderer
This study presents the first structural description of the fusobacterial TAA CbpF and its interaction with CEACAM1, revealing a novel binding mode and potential targets for drug design in CRC.
Proceedings of the National Academy of Sciences · Apr 8, 2025Peer-reviewedBiophysics