Author

Gian Luca Marongiu

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0009-0006-3788-0664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Daniel RodereriD· 2 shared Felix SchöpfiD· 2 shared Andreas OderiD· 1 shared Annette MoteriD· 1 shared Jens Peter von KriesiD· 1 shared Judith KikhneyiD· 1 shared Klaudia Milaj· 1 shared Thiemo SprinkiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

Daniel RodererORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 29, 2025

Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Felix Schöpf, Gian Luca Marongiu, Klaudia Milaj…·Daniel Roderer

This study determines the structural basis of Fusobacterium nucleatum adhesin Fap2 interactions with Gal-GalNAc and TIGIT, revealing binding mechanisms and structural details.

33 citationstop 2%

humanstructural biology

𝕏 PostBluesky

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedApr 8, 2025

Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF

Gian Luca Marongiu, Uwe Fink, Felix Schöpf…·Daniel Roderer

This study presents the first structural description of the fusobacterial TAA CbpF and its interaction with CEACAM1, revealing a novel binding mode and potential targets for drug design in CRC.

9 citations

humancryo-EM

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