Author

V. A. Co

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

H. El-Nezami· 3 shared M. L. Y. Wan· 2 shared B. Twum· 1 shared D. Zhao· 1 shared M. L. Wan· 1 shared M. Sabzichi· 1 shared P. A. Cox· 1 shared P. C. Turner· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersPharmacology & Toxicology

H. El-Nezami

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deoxynivalenol induced inflammation and increased the adherence of entero-invasive Escherichia coli to intestinal epithelial cells via modulation of mucin and pro-inflammatory cytokine production

M. L. Wan, V. A. Co, P. C. Turner, S. P. Nagendra, H. El-Nezami

This study shows that deoxynivalenol increases EIEC adherence to intestinal cells by modulating mucins and pro-inflammatory cytokines.

bioRxiv · Mar 11, 2024 · PreprintPharmacology & Toxicology

Schisandrin B suppresses colon cancer growth by inducing cell cycle arrest and apoptosis via the CHOP signalling pathway

V. A. Co, H. El-Nezami, Y. Liu, B. Twum, P. Dey, P. A. Cox, S. Joseph, R. Agbodjan, M. Sabzichi, R. Draheim, M. L. Y. Wan

This study identifies Schisandrin B's mechanism of action in colon cancer, showing it induces cell cycle arrest and apoptosis via the CHOP signalling pathway.

bioRxiv · Aug 27, 2023 · PreprintPharmacology & Toxicology

Bioavailability of Schisandrin B and its effect on 5-Fluorouracil metabolism in a xenograft mouse model of colorectal cancer

P.-K. Lee, V. A. Co, Y. Yang, M. L. Y. Wan, H. El-Nezami, D. Zhao

This study shows Schisandrin B enhances 5-Fluorouracil efficacy in colorectal cancer by modulating drug metabolism and reducing multidrug resistance.

bioRxiv · Nov 28, 2022 · PreprintPharmacology & Toxicology