Author

V. A. G. Lopez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

L. Plate· 2 shared A. B. Gonzalez· 1 shared A. Criollo· 1 shared B. B. Maitre· 1 shared B. Timalsina· 1 shared C. Hetz· 1 shared E. Jokitalo· 1 shared F. Aprahamia· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

L. Plate

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis

Y. Hazari, H. Urra, V. A. G. Lopez, J. Diaz, G. Tamburini, M. Milani, P. Pihan, S. Durand, F. Aprahamia, R. Baxter, M. Huang, X. C. Dong, H. Vihinen, A. B. Gonzalez, P. Godoy, , C. Hetz

This study shows that IRE1 regulates collagen secretion via P4HB, contributing to liver fibrosis in models of CCl4 and high fat diet.

bioRxiv · May 2, 2023 · PreprintCell Biology

Time-Resolved Interactome Profiling Deconvolutes Secretory Protein Quality Control Dynamics

M. T. Wright, B. Timalsina, V. A. G. Lopez, J. N. Hermanson, S. Garcia, L. Plate

This study develops TRIP, a mass-spectrometry method to map protein interactions over time, and applies it to study hypothyroidism by analyzing thyroglobulin interactions and identifying VCP and TEX264 as key factors in protein degradation.

bioRxiv · Sep 4, 2022Cell Biology