Author

V. B. O'Donnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Williams· 2 shared V. Tyrrell· 2 shared A. Engler· 1 shared A. J. Harwood· 1 shared A. O'Connor· 1 shared A. Pryce Roberts· 1 shared B. McAllister· 1 shared C. Hinz· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

J. Williams

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2 papers

Recent·Most cited

Upregulated NF-κB pathway proteins may underlie APOE4 associated astrocyte phenotypes in sporadic Alzheimer's disease

A. Pryce Roberts, K. Dec, B. McAllister, V. Tyrrell, V. B. O'Donnell, A. J. Harwood, J. Williams

This study identifies APOE44-associated astrocyte phenotypes in Alzheimer's disease, linking them to upregulated NF-κB pathway proteins.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274

S. Meckelmann, J. Hawksworth, D. White, R. Andrews, P. Rodrigues, A. O'Connor, J. Alvarez Jarreta, V. Tyrrell, C. Hinz, Y. Zhou, J. Williams, M. Aldrovandi, W. J. Watkins, A. Engler, D. Slatter, , V. B. O'Donnell

The paper identifies metabolic dysregulation of lysophospholipid/autotaxin pathways linked to a CHD risk SNP, showing altered lipid metabolism and enzyme expression in multiple models.

bioRxiv · Oct 2, 2019Physiology