The MALDI TOF E2/E3 ligase assay as an universal tool for drug discovery in the ubiquitin pathway
V. De Cesare, C. Johnson, V. Barlow, J. Hastie, A. Knebel, M. Trost
The paper introduces a MALDI TOF-based assay for high-throughput screening of E2/E3 ligase activity in the ubiquitin pathway, demonstrating its utility for drug discovery.
bioRxiv · Nov 29, 2017Biochemistry