Author

V. Bitko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Fattom· 3 shared S. Ganesan· 3 shared C. Chen· 2 shared C.-E. Lien· 2 shared K. Trabbic· 2 shared M.-Y. Lin· 2 shared Y.-J. Lin· 2 shared Y.-S. Chuang· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

A. Fattom

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhancing Polysaccharide Immunity through Intranasal Immunizations

K. Trabbic, S. Ganesan, A. Fattom, A. Lees, V. Bitko

This study evaluates a polysaccharide conjugate vaccine with NE01 adjuvant for intranasal immunization, showing robust IgG/IgA responses and enhanced Th1/Th2/Th17 immunity against S. pneumonia.

bioRxiv · Apr 19, 2022 · PreprintImmunology

Intranasal Nanoemulsion Adjuvanted S-2P Vaccine Demonstrates Protection in Hamsters and Induces Systemic, Cell-Mediated and Mucosal Immunity in Mice

S. Ganesan, H. Acosta, C. Brigolin, K. Orange, K. Trabbic, C. Chen, C.-E. Lien, Y.-J. Lin, M.-Y. Lin, Y.-S. Chuang, A. Fattom, V. Bitko

This study shows an intranasal nanoemulsion-adjuvanted S-2P vaccine induces strong systemic, cell-mediated, and mucosal immunity in mice and protects hamsters from SARS-CoV-2 infection.

bioRxiv · Mar 22, 2022Immunology

Protection of Hamsters Challenged with SARS-CoV-2 after Two Doses of MVC-COV1901 Vaccine Followed by a Single Intranasal Booster with Nanoemulsion Adjuvanted S-2P Vaccine

Y.-J. Lin, M.-Y. Lin, Y.-S. Chuang, L. T. C. Liu, T.-Y. Kuo, C. Chen, S. Ganesan, A. Fattom, V. Bitko, C.-E. Lien

This study shows that a two-dose intramuscular vaccine followed by an intranasal booster provides strong protection against SARS-CoV-2 in hamsters, reducing viral load and disease symptoms.

bioRxiv · Feb 24, 2022Immunology

Regulation of NF-kappa B and cell death by bacterial gingipains

S. Urnowey, T. Ansai, V. Bitko, S. Barik

This study shows that P. gingivalis gingipains promote apoptosis in HGF cells by cleaving procaspase-3, while a triple protease mutant fails to induce apoptosis.

bioRxiv · Feb 25, 2020 · PreprintMicrobiology