Author

V. Broccoli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Iannielli· 1 shared A. Sessa· 1 shared B. Bellinazzi· 1 shared C. Laura· 1 shared C. Palma· 1 shared C. Perucchini· 1 shared D. Marotta· 1 shared E. Bono· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBioengineering

A. Iannielli

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

S. G. Giannelli, M. Luoni, B. Bellinazzi, A. Iannielli, J. Middeldorp, I. Philippens, J. Korbelin, V. Broccoli

This study develops two new AAV9 variants with improved brain targeting and reduced liver off-targeting by modifying the galactose-binding domain and displaying peptides.

bioRxiv · Jun 27, 2023Bioengineering

Controlled administration of aerosolized SARS-CoV-2 to K18-hACE2 transgenic mice uncouples respiratory infection and anosmia from fatal neuroinvasion

V. Fumagalli, M. Rava, D. Marotta, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. Garcia-Manteiga, L. Donnici, L. Manganaro, , M. Iannacone

This study develops an aerosolized SARS-CoV-2 infection model in K18-hACE2 mice that replicates respiratory symptoms without fatal neuroinvasion, offering a more accurate representation of human COVID-19 pathogenesis.

bioRxiv · Aug 6, 2021Immunology

A human stem cell-derived neurosensory-epithelial circuitry on-a-chip to model herpes simplex virus reactivation

P. G. Mazzara, E. Criscuolo, M. Rasponi, L. Massimino, S. Muggeo, C. Palma, M. Castelli, M. Clementi, R. Burioni, N. Mancini, V. Broccoli, N. Clementi

This study develops a human stem cell-derived neurosensory-epithelial circuitry on-a-chip to model HSV-1 reactivation and latency.

bioRxiv · Nov 19, 2020Microbiology