Author

V. Dubey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

H. Khandelia· 3 shared A. AHMAD· 1 shared B. Bozorg· 1 shared B. P. Pedersen· 1 shared B. S. Ahluwalia· 1 shared D. L. Stokes· 1 shared D. S. MEHTA· 1 shared D. WOLFSON· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

H. Khandelia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An intracellular pathway controlled by the N-terminus of the pump subunit inhibits the bacterial KdpFABC ion pump in high K+ conditions

H. Khandelia, D. L. Stokes, B. P. Pedersen, V. Dubey

This study uses molecular dynamics simulations to show phosphorylation of KdpB traps it in an inactive conformation by hydrating the ion-binding site via an intracellular pathway.

bioRxiv · Jan 13, 2021Biophysics

Quantitative assessment of morphology and sub-cellular changes in macrophages and trophoblasts during inflammation

R. SINGH, V. DUBEY, D. WOLFSON, A. AHMAD, G. ACHARYA, A. AHMAD, D. S. MEHTA, P. BASNET, B. S. Ahluwalia

The paper quantifies morphological and sub-cellular changes in macrophages and trophoblasts during inflammation using advanced microscopy and machine learning to detect inflammation with high accuracy.

bioRxiv · Jan 27, 2020Cell Biology

Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain

V. Dubey, B. Bozorg, D. Wuestner, H. Khandelia

This study shows that cholesterol binding to the SSD of NPC1 restricts NTD dynamics, suggesting an allosteric feedback mechanism regulating lysosomal cholesterol levels.

bioRxiv · Nov 25, 2019Biophysics

A single K+-binding site in the crystal structure of the gastric proton pump

K. Yamamoto, V. Dubey, K. Irie, H. Nakanishi, H. Khandelia, Y. Fujiyoshi, K. Abe

The paper determines the crystal structure of the gastric proton pump, revealing a single K+-binding site and confirming a 1H+/1K+ exchange per ATP hydrolysis.

bioRxiv · Apr 15, 2019Biochemistry