A Zika vaccine based on chimpanzee adenovirus ChAdOx1 elicits lineage-transcending sterile immunity and prevents colonisation of brain and ovaries
C. Lopez-Camacho, S. Dowall, V. Graham, S. Findlay-Wilson, E. Rayner, Y. Chan Kim, R. Hewson, A. Reyes-Sandoval
This paper evaluates a ZIKV vaccine based on chimpanzee adenovirus ChAdOx1, showing it provides sterile immunity against both Asian and African lineages and prevents viral colonization of brain and ovaries.
bioRxiv · Jan 14, 2019 · PreprintPathology