Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype
B. Hommel, A. Sturny-Leclere, S. Volant, N. Veluppillai, M. Duchateau, C.-H. Yu, V. Hourdel, H. Varet, M. Matondo, J. R. Perfect, A. Casadevall, F. Dromer, A. Alanio
This paper demonstrates that Cryptococcus neoformans can enter a viable but non-culturable state under specific in vitro conditions, characterized by reduced metabolism and reactivation potential.
bioRxiv · Jun 29, 2019Microbiology