M. Duchateau

The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile

This study identifies CD1687 as a DNA-binding lipoprotein required for DCA-induced biofilm formation in C. difficile by promoting cell-matrix interactions through eDNA binding.

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

This study shows that Q34 modification in tRNA affects translational efficiency in Vibrio cholerae under aminoglycoside stress, leading to reprogramming of gene expression and antibiotic tolerance.

Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes

This study shows that NAD kinase in Staphylococcus aureus supports virulence factor production and survival in host immune cells, reducing zebrafish mortality when inhibited.

Universal amyloidogenicity of patient-derivedimmunoglobulin light chains

This study shows that all tested patient-derived immunoglobulin light chains have comparable amyloidogenic potential, with proteolytic cleavage being a key determinant of in vivo aggregation.

The Flemmingsome reveals an ESCRT-to-membrane coupling required for completion of cytokinesis

The paper identifies a plasma membrane-to-ESCRT module essential for abscission, showing its role in cytokinesis, exosome formation, and HIV budding.

Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype

This paper demonstrates that Cryptococcus neoformans can enter a viable but non-culturable state under specific in vitro conditions, characterized by reduced metabolism and reactivation potential.

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis

This study shows that TG2 activation during Chlamydia trachomatis infection enhances glucose uptake and hexosamine biosynthesis to support bacterial growth.