Author

V. McGaughey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Capobianco· 1 shared G. Seraphin· 1 shared J. Heckel· 1 shared K. L. Nguyen· 1 shared K. Schesser· 1 shared L. Padula· 1 shared M. Arons· 1 shared M. Wylie· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

E. Capobianco

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2 papers

Recent·Most cited

Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition

E. Capobianco, V. McGaughey, G. Seraphin, J. Heckel, S. Rieger, T. S. Lisse

This study shows vitamin D inhibits osteosarcoma by suppressing NMD, EMT, and ROS through VDR signaling and SNAI2 downregulation, with calcipotriol reducing metastasis in mice.

bioRxiv · Jan 4, 2023Cancer Biology

Perforin-2 limits pathogen proliferation at the maternal-fetal interface

P. Gayle, V. McGaughey, R. Hernandez, K. L. Nguyen, M. Arons, L. Padula, N. Strbo, M. Wylie, R. C. Colletti, K. Schesser

This study shows Perforin-2 protects against Listeria monocytogenes in the placenta, with maternal and fetal contributions, and its expression is induced in decidual macrophages during high-dose infections.

bioRxiv · May 20, 2020 · PreprintImmunology