NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
Z.-J. XIAO, J. Liu, S.-Q. Wang, Y. Zhu, X.-Y. Gao, V. P.-C. Tin, J. Qin, J.-W. Wang, M. P. Wong
This study identifies NFATc2 as a regulator of lung tumor-initiating cells via the NFATc2/SOX2/ALDH1A1 axis, linking it to drug resistance and poor patient outcomes.
bioRxiv · Apr 28, 2017Cancer Biology