Z.-J. Xiao

Macropinosomes host TLR9 signaling and regulation of inflammatory responses in microglia

This study shows that TLR9 signaling in microglia occurs in macropinosomes, which regulate inflammatory responses through co-receptors and regulators.

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

This study identifies NFATc2 as a regulator of lung tumor-initiating cells via the NFATc2/SOX2/ALDH1A1 axis, linking it to drug resistance and poor patient outcomes.