V. Palanisamy

Loss of CPAP expression promotes sustained EGFR signaling and Epithelial-Mesenchymal Transition in oral cancer cells

This study shows that loss of CPAP increases EGFR signaling and promotes EMT and invasiveness in OSCC cells, which can be reversed by EGFR depletion.

Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR

This study shows CPAP promotes endocytic transport and lysosome targeting of EGFR by facilitating its movement from early to late endosomes and MVBs.