Author

V. Pedergnana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:human· 2 Research Focus:phylogenetics / evolution· 2 Approach:Bayesian inference· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. Barnes· 2 shared M. A. Ansari· 2 shared STOP-HCV Consortium· 2 shared A. Ansari· 1 shared A. Magri· 1 shared A. Miles· 1 shared A. Tellier· 1 shared B. Wertheim· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

E. Barnes

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Author profile →

4 papers

Recent·Most cited

Mitochondrial variation in Anopheles gambiae and An. coluzzii: phylogeographic legacy of species isolation and mito-nuclear associations with metabolic resistance to pathogens and insecticides

J. E. Amaya Romero, C. Chenal, Y. Ben Chehida, A. Miles, C. S. Clarkson, V. Pedergnana, B. Wertheim, M. C. Fontaine

The paper analyzes mitochondrial DNA variation in Anopheles gambiae and An. coluzzii, revealing phylogeographic patterns and mito-nuclear associations with metabolic resistance.

bioRxiv · Jul 18, 2023 · PreprintEvolutionary Biology

Inference of host-pathogen interaction matrices from genome-wide polymorphism data

H. Maerkle, S. John, L. Metzger, STOP-HCV Consortium, M. A. Ansari, V. Pedergnana, A. Tellier

This paper develops a Bayesian method to infer host-pathogen interaction matrices from genome-wide polymorphism data and applies it to HCV-infected humans to identify new resistance genes and GxG interactions.

bioRxiv · Jul 6, 2023Evolutionary Biology

Global spread and evolutionary history of HCV subtype 3a

S.-K. Lin, N. De Maio, V. Pedergnana, C.-H. Wu, J. Theze, E. Barnes, A. Ansari

The paper uses host and virus genomic data to trace the global spread and evolutionary history of HCV subtype 3a, finding it originated in South Asia and spread through three independent events post-World War II.

bioRxiv · Feb 3, 2021 · PreprintEvolutionary Biology

Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

D. A. Smith, A. Magri, R. Bowden, N. Chaturvedi, J. Fellay, J. McLauchlan, G. R. Foster, W. L. Irving, STOP-HCV Consortium, P. Simmonds, V. Pedergnana, E. Barnes, M. A. Ansari

This study identifies three HCV polymorphisms in NS2 and NS3 proteins associated with sofosbuvir treatment failure using whole genome sequencing of 507 patients.

bioRxiv · May 5, 2020Microbiology