Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
D. A. Smith, A. Magri, R. Bowden, N. Chaturvedi, J. Fellay, J. McLauchlan, G. R. Foster, W. L. Irving, STOP-HCV Consortium, P. Simmonds, V. Pedergnana, E. Barnes, M. A. Ansari
This study identifies three HCV polymorphisms in NS2 and NS3 proteins associated with sofosbuvir treatment failure using whole genome sequencing of 507 patients.
bioRxiv · May 5, 2020Microbiology