Author

M. A. Ansari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Assay:whole-genome sequencing· 3 Approach:Bayesian inference· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Barnes· 3 shared P. C. Matthews· 2 shared R. Bowden· 2 shared STOP-HCV Consortium· 2 shared V. Pedergnana· 2 shared A. Brown· 1 shared A. J. Pollard· 1 shared A. L. McNaughton· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

E. Barnes

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Author profile →

5 papers

Recent·Most cited

Inference of host-pathogen interaction matrices from genome-wide polymorphism data

H. Maerkle, S. John, L. Metzger, STOP-HCV Consortium, M. A. Ansari, V. Pedergnana, A. Tellier

This paper develops a Bayesian method to infer host-pathogen interaction matrices from genome-wide polymorphism data and applies it to HCV-infected humans to identify new resistance genes and GxG interactions.

bioRxiv · Jul 6, 2023Evolutionary Biology

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations

J. Mokaya, T. I. Vasylyeva, E. Barnes, M. A. Ansari, O. G. Pybus, P. C. Matthews

This study analyzes the global prevalence and phylogeny of HBV drug and vaccine resistance mutations, finding high prevalence in genotype C and evidence of independent emergence of resistance mutations.

bioRxiv · Oct 7, 2020Evolutionary Biology

Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

D. A. Smith, A. Magri, R. Bowden, N. Chaturvedi, J. Fellay, J. McLauchlan, G. R. Foster, W. L. Irving, STOP-HCV Consortium, P. Simmonds, V. Pedergnana, E. Barnes, M. A. Ansari

This study identifies three HCV polymorphisms in NS2 and NS3 proteins associated with sofosbuvir treatment failure using whole genome sequencing of 507 patients.

bioRxiv · May 5, 2020Microbiology

Analysis of genomic-length HBV sequences to determine genotype and subgenotype reference sequences

A. L. McNaughton, P. Revill, M. Littlejohn, P. C. Matthews, M. A. Ansari

The paper generates updated HBV genotype and subgenotype reference sequences using phylogenetic analysis of genomic-length sequences from public databases.

bioRxiv · Nov 8, 2019Microbiology

Targeted metagenomic sequencing enhances the identification of pathogens associated with acute infection.

C. Goh, T. Golubchik, M. A. Ansari, M. de Cesare, A. Trebes, I. Elliott, D. Bonsall, P. Piazza, A. Brown, H. Slawinski, N. Martin, S. Defres, M. J. Griffiths, J. E. Bray, M. C. Maiden, , R. Bowden

Castanet, a targeted metagenomic sequencing method, improves pathogen detection in clinical samples by combining sensitivity with cost-effectiveness and broad organism coverage.

bioRxiv · Jul 28, 2019 · PreprintMicrobiology