NEIL2 plays a critical role in limiting inflammation and preserving genomic integrity in H. pylori-infected gastric epithelial cells
A. Z. Sahan, T. Venkova, I. M. Sayed, E. Beswick, V. Reyes, I. Pinchuk, D. Sahoo, P. Ghosh, T. K. Hazra, S. Das
This study shows that NEIL2 suppression by H. pylori infection leads to DNA damage accumulation, inflammation, and gastric cancer progression in mouse models and human cells.
bioRxiv · Jul 2, 2019 · PreprintMicrobiology