Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
A. K. Ajay, L. Zhao, S. Vig, M. Fujiwara, S. Thakurela, S. Jadhav, I.-J. Chiu, Y. Ding, K. K. Ramachandran, A. Mittal, A. Bhatt, P. Chaluvadi, M. K. Gupta, V. S. Sabbisetti, A. M. Waaga-Gasser, , L.-L. Hsiao
This study shows that deleting STAT3 in stromal cells prevents kidney fibrosis by blocking pericyte trans-differentiation and migration.
bioRxiv · Aug 19, 2021 · PreprintCell Biology