S. Jadhav

Exploring respiratory viral pathogens and bacteriome from symptomatic SARS-CoV-2-negative and positive individuals

This study identifies co-infections with other respiratory viruses and bacteria in SARS-CoV-2-positive and negative patients, finding higher viral infections in negatives and specific bacterial phyla in both groups.

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

This study shows that deleting STAT3 in stromal cells prevents kidney fibrosis by blocking pericyte trans-differentiation and migration.

Pre-metastatic niche drives breast cancer invasion by modulating MSC homing and CAF differentiation

The paper shows that pre-metastatic niche modulates MSC homing and CAF differentiation, promoting breast cancer invasion and metastasis.

Amyloid fibril-based hydrogels for high-throughput tumor spheroid modeling

This paper develops amyloid fibril-based hydrogels for 3D tumor spheroid modeling, showing enhanced drug resistance and cancer biomarker expression compared to 2D cultures.

Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

This study measures flagellar energetics in mouse sperm using high-speed imaging and computational models, finding that internal dissipation dominates over hydrodynamic losses and that Crisp2-knockout mice show reduced power and motility.

Induction of intracellular wild-type p53 amyloids leading to cellular transformation and tumor formation in mice

This study shows that wild-type p53 amyloid formation leads to cellular transformation and tumor formation in mice by enhancing survival, proliferation, and migration while suppressing tumor suppressors.

Comparison of two commercial ELISA kits for detection of rubella specific IgM and IgG antibodies

This study compares two ELISA kits for detecting rubella-specific IgM and IgG antibodies, finding good qualitative agreement and suggesting Euroimmun as a viable alternative.