Author

J. V. Bonventre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

L. Li· 2 shared M. T. Valerius· 2 shared P. Galichon· 2 shared A. Bhatt· 1 shared A. C. Figueroa-Ramirez· 1 shared A. K. Ajay· 1 shared A. M. Waaga-Gasser· 1 shared A. Mittal· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

L. Li

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stromal-cell deletion of STAT3 protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

A. K. Ajay, L. Zhao, S. Vig, M. Fujiwara, S. Thakurela, S. Jadhav, I.-J. Chiu, Y. Ding, K. K. Ramachandran, A. Mittal, A. Bhatt, P. Chaluvadi, M. K. Gupta, V. S. Sabbisetti, A. M. Waaga-Gasser, , L.-L. Hsiao

This study shows that deleting STAT3 in stromal cells prevents kidney fibrosis by blocking pericyte trans-differentiation and migration.

bioRxiv · Aug 19, 2021 · PreprintCell Biology

Orphan nuclear receptor COUP-TFII drives the myofibroblast metabolic shift leading to fibrosis

L. Li, P. Galichon, X. Xiao, A. C. Figueroa-Ramirez, D. Tamayo, J. J. Lee, M. Kalocsay, D. Gonzalez-Sanchez, M. S. Chancay, K. McCracken, D. Lemos, N. Lee, T. Ichimura, Y. Mori, M. T. Valerius, , J. V. Bonventre

This study identifies COUP-TFII as a driver of myofibroblast metabolic shift to aerobic glycolysis, promoting fibrosis in multiple organs.

bioRxiv · Jun 5, 2020 · PreprintCell Biology

Proliferation impairs cell viability via energy depletion

P. Galichon, M. Lannoy, L. Li, S. Vandermeersch, D. Legouis, M. T. Valerius, J. Hadchouel, J. V. Bonventre

The paper shows that proliferation in kidney cells reduces energy availability, leading to cell death and chronic kidney disease under metabolic stress.

bioRxiv · Apr 24, 2020 · PreprintPhysiology