Author

V. Viswanadham

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

D. J. Irvine· 1 shared E. Demissie· 1 shared F. Alsufyani· 1 shared G. J. Yuen· 1 shared J. J. Moon· 1 shared J. Q. Tran· 1 shared S. Kumari· 1 shared S. Pillai· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

D. J. Irvine

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1 paper

Recent·Most cited

DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering

E. Demissie, V. Mahajan, F. Alsufyani, S. Kumari, G. J. Yuen, V. Viswanadham, J. Q. Tran, J. J. Moon, D. J. Irvine, S. Pillai

This study shows that DOCK2 deficiency leads to increased virtual memory CD8+ T cells by enhancing TCR sensitivity to weak agonists and reducing tonic TCR triggering.

bioRxiv · Mar 20, 2019Immunology