Author

G. J. Yuen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

H. Mattoo· 3 shared S. Pillai· 3 shared N. Sun· 2 shared V. Mahajan· 2 shared V. S. Mahajan· 2 shared V. V. Viswanadham· 2 shared C. Annaiah· 1 shared D. J. Irvine· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

H. Mattoo

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4 papers

Recent·Most cited

Network-based integration of epigenetic landscapes unveils molecular programs underlying human T follicular helper cell differentiation

V. S. Mahajan, S. A. Rahman, V. V. Viswanadham, G. J. Yuen, N. Sun, H. Mattoo, S. S. Pillai, J. Das

The paper integrates epigenomic data with a protein interactome to identify molecular programs driving human Tfh cell differentiation and links these to immune signaling in severe COVID-19.

bioRxiv · May 19, 2021 · PreprintImmunology

B1 and B2 B cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers

V. S. Mahajan, H. Mattoo, N. Sun, V. V. Viswanadham, G. J. Yuen, H. Allard-Chamard, M. Ahmad, S. J. H. Murphy, C. Annaiah, Y. Tuncay, S. Pillai

The paper identifies distinct CpG modification states in B1 and B2 B cells at DNMT3A-maintained enhancers, showing differential methylation dynamics during development.

bioRxiv · Apr 30, 2020Immunology

DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering

E. Demissie, V. Mahajan, F. Alsufyani, S. Kumari, G. J. Yuen, V. Viswanadham, J. Q. Tran, J. J. Moon, D. J. Irvine, S. Pillai

This study shows that DOCK2 deficiency leads to increased virtual memory CD8+ T cells by enhancing TCR sensitivity to weak agonists and reducing tonic TCR triggering.

bioRxiv · Mar 20, 2019Immunology

The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

S. Pillai, J. Stone, S. Nakamura, T. Kiyoshima, J. Daccache, M. Yamauchi, H. Yamamoto, T. Saeki, M. Moriyama, M. Ohta, N. Ishiguro, G. J. Yuen, S. L. Murphy, V. Mahajan, H. Mattoo, T. Maehara

The paper identifies IL-4+ BATF+ T follicular helper cells in IgG4-related disease that correlate with IgG4 class switching in lymphoid organs.

bioRxiv · Mar 19, 2018Immunology