Heterogeneity of satellite cells implicates DELTA1/ NOTCH2 signaling in self-renewal
V. Yartseva, L. D. Goldstein, J. Rodman, L. Kates, M. Z. Chen, Y.-J. J. Chen, O. Foreman, C. W. Siebel, Z. Modrusan, A. S. Peterson, A. Jovicic
The paper identifies DELTA1/NOTCH2 signaling as critical for satellite cell self-renewal during muscle regeneration by analyzing single-cell RNA sequencing data and using antagonistic antibodies.
bioRxiv · Oct 30, 2019Cell Biology