Author

M. Z. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

A. Jovicic· 1 shared A. S. Peterson· 1 shared C. S. McGinnis· 1 shared C. W. Siebel· 1 shared D. M. Patterson· 1 shared D. Yang· 1 shared E. D. Chow· 1 shared F. Horns· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Jovicic

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Author profile →

2 papers

Recent·Most cited

Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution

D. Yang, M. G. Jones, S. Naranjo, W. M. Rideout, K. H. J. Min, R. Ho, W. Wu, J. M. Replogle, J. L. Page, J. J. Quinn, F. Horns, X. Qiu, M. Z. Chen, W. A. Freed-Pastor, C. S. McGinnis, , J. S. Weissman

The paper tracks tumor evolution in a mouse model using lineage tracing and single-cell RNA-seq, revealing plasticity, fitness-associated programs, and stereotypical evolutionary trajectories.

bioRxiv · Oct 12, 2021 · PreprintCancer Biology

Heterogeneity of satellite cells implicates DELTA1/ NOTCH2 signaling in self-renewal

V. Yartseva, L. D. Goldstein, J. Rodman, L. Kates, M. Z. Chen, Y.-J. J. Chen, O. Foreman, C. W. Siebel, Z. Modrusan, A. S. Peterson, A. Jovicic

The paper identifies DELTA1/NOTCH2 signaling as critical for satellite cell self-renewal during muscle regeneration by analyzing single-cell RNA sequencing data and using antagonistic antibodies.

bioRxiv · Oct 30, 2019Cell Biology