Pharmacology & ToxicologybioRxivPreprint
Cyanine dye conjugates of a 2'-deoxycytidine-based auto- and mitophagy activator extend Caenorhabditis elegans lifespan
Ekaterina A. Guseva, Polina N. Kamzeeva, Sofya Y. Sokolskaya…·Andrey V. Aralov
The paper identifies a 2'-deoxycytidine-based compound that activates autophagy and mitophagy, extends C. elegans lifespan when conjugated with a mitochondria-targeting dye.