Author

Valery A. Shepelev

Institute of Molecular Genetics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 5

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 5 Approach:experimental assay· 4 Organism:human· 4 Research Focus:database / resource· 3 Approach:statistical model· 3 Research Focus:genome assembly· 2 Organism:non-human primate· 2 Research Focus:phylogenetics / evolution· 2

Frequent Co-Authors

Adam M. PhillippyiD· 5 shared Evan E. EichleriD· 5 shared Fedor RyaboviD· 5 shared Ivan A. AlexandroviD· 5 shared Glennis A. LogsdoniD· 4 shared Jennifer L. GertoniD· 4 shared Karen H. MigaiD· 4 shared Sergey KoreniD· 4 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Adam M. PhillippyORCID

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5 papers

Recent·Most cited

Comparative genomics of macaques and integrated insights into genetic variation and population history

Shilong Zhang, Ning Xu, Lianting Fu, Xiangyu Yang, Kaiyue Ma, Yamei Li, Zikun Yang, Zhengtong Li, Yu Feng, Xinrui Jiang, Junmin Han, Ruixing Hu, Lu Zhang, Duan Lian, Luciana de Gennaro, , Yafei Mao

This study presents genome assemblies and analyses of macaques to explore genetic variation, population history, and evolutionary differences between species and humans.

Nature · Feb 26, 2025Peer-reviewedGenomics

The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes

Kateryna D. Makova, Brandon D. Pickett, Robert S. Harris, Gabrielle A. Hartley, Monika Čechová, Karol Pál, Sergey Nurk, DongAhn Yoo, Qiuhui Li, Prajna Hebbar, Barbara C. McGrath, Francesca Antonacci, Margaux Aubel, Arjun Biddanda, Matthew Borchers, , Adam M. Phillippy

The paper produces gapless assemblies of ape sex chromosomes for five great apes and a lesser ape, revealing divergence in Y chromosomes and evolutionary dynamics.

Nature · May 29, 2024Peer-reviewedGenomics

The variation and evolution of complete human centromeres

Glennis A. Logsdon, Allison N. Rozanski, Fedor Ryabov, Tamara Potapova, Valery A. Shepelev, Claudia Rita Catacchio, David Porubskỳ, Yafei Mao, DongAhn Yoo, Mikko Rautiainen, Sergey Koren, Sergey Nurk, Julian Lucas, Kendra Hoekzema, Katherine M. Munson, , Evan E. Eichler

A second complete human centromere set (CHM1) plus 31 nonhuman primate centromeres reveals extensive α-satellite higher-order repeat variation, kinetochore repositioning, and saltatory emergence of new repeats.

Nature · Apr 3, 2024Peer-reviewedGenomics✦ In-depth digest

The complete sequence of a human Y chromosome

Arang Rhie, Sergey Nurk, Monika Čechová, Savannah J. Hoyt, Dylan J. Taylor, Nicolas Altemose, Paul W. Hook, Sergey Koren, Mikko Rautiainen, Ivan A. Alexandrov, Jamie Allen, Mobin Asri, Andrey V. Bzikadze, Nae-Chyun Chen, Chen-Shan Chin, , Adam M. Phillippy

The paper presents the complete sequence of a human Y chromosome, correcting errors in the GRCh38 reference and adding over 30 million base pairs.

Nature · Aug 23, 2023Peer-reviewedGenomics

Complete genomic and epigenetic maps of human centromeres

Nicolas Altemose, Glennis A. Logsdon, Andrey V. Bzikadze, Pragya Sidhwani, Sasha A. Langley, Gina Viviana Caldas, Savannah J. Hoyt, Lev I. Uralsky, Fedor Ryabov, Colin J. Shew, Michael E.G. Sauria, Matthew Borchers, Ariel Gershman, Alla Mikheenko, Valery A. Shepelev, , Karen H. Miga

The paper presents a comprehensive analysis of fully assembled human centromeres, revealing their architecture, variation, and evolutionary dynamics at high resolution.

Science · Mar 31, 2022Peer-reviewedGenomics