An in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
Léa Pinon, Mélanie Chabaud, Pierre Nivoit, Jérôme Wong-Ng, Tri Tho Nguyen, Vanessa Paul, Charlotte Bouquerel, Sylvie Goussard, Pauline Smilovici, Emmanuel Frachon, Dorian Obino, Samy Gobaa, Guillaume Duménil
This paper develops a 3D microfluidic model to study Neisseria meningitidis colonization and vascular damage, showing it replicates in vivo infection features with higher resolution than animal or 2D models.
eLife · Dec 17, 2025Peer-reviewedSynthetic Biology