Guillaume Duménil

This study shows that Neisseria meningitidis uses ancreopodia to transmit mechanical forces from the apical surface to the basal extracellular matrix, altering host-cell mechanics.

This study shows neutrophils maintain high migration speed in capillaries of varying sizes by adapting their actomyosin cytoskeleton via the ROCK-MyoII pathway, preventing vascular obstruction.

The paper introduces an automated framework for optimizing bacterial tracking pipelines using TrackMate 8, demonstrating its effectiveness on two use cases.

This paper develops a 3D microfluidic model to study Neisseria meningitidis colonization and vascular damage, showing it replicates in vivo infection features with higher resolution than animal or 2D models.

Rewritten Fiji plugin TrackMate now uses StarDist, ilastik, Weka, MorphoLibJ or imported label images as detectors, stores 2D object contours, and tracks shape and intensity over time.

This study identifies a novel physical mechanism, 1D wetting, by which Neisseria meningitidis drives plasma membrane remodeling on nanofibers independent of F-actin.