Sylvie Goussard

This study shows that Neisseria meningitidis uses ancreopodia to transmit mechanical forces from the apical surface to the basal extracellular matrix, altering host-cell mechanics.

This study shows that bacterial growth under confinement leads to increased turgor pressure, which disrupts division and protein synthesis, and activates the Rcs pathway, with implications for infection physiology.

This paper develops a 3D microfluidic model to study Neisseria meningitidis colonization and vascular damage, showing it replicates in vivo infection features with higher resolution than animal or 2D models.

This study identifies a novel physical mechanism, 1D wetting, by which Neisseria meningitidis drives plasma membrane remodeling on nanofibers independent of F-actin.