Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability
Adam K. Hedger, Wazo Myint, Jeong Min Lee, Diego Suchenski Loustaunau, Vanivilasini Balachandran, Ala M. Shaqra, Neşe Kurt Yılmaz, Jonathan K. Watts, Hiroshi Matsuo, Celia A. Schiffer
This study designs and tests optimized oligonucleotide inhibitors for APOBEC3 enzymes, showing improved potency and nuclease stability compared to previous inhibitors.
Nucleic Acids Research · Mar 16, 2025Peer-reviewedBiochemistry