BioengineeringbioRxivPreprint
One-Pot NADH-Mediated Physiological Redox-Controlled Synthesis of Papain-Stabilized Copper Nanoclusters with Preserved Bioactivity for Efficient Drug Delivery
Aman Singh, Ananya Anand, Vanshika Vanshika…·Shirsendu Ghosh
This paper develops a one-pot, physiologically compatible synthesis of papain-stabilized copper nanoclusters using NADH as a reducing agent, showing enhanced helical stability and effective drug delivery with reduced IC50 in cancer cells.
DOI 10.64898/2026.04.20.719779