Author

Aman Singh

Western University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Hien Chi NguyeniD· 3 shared Krishna Kumar SinghiD· 3 shared Ananya AnandiD· 1 shared Anujit Balo· 1 shared Bharatsinai Peddi· 1 shared Christina A. CastellaniiD· 1 shared Dr. Farhan Ahmed· 1 shared Koyel Banerjee-Ghosh· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

Hien Chi NguyenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Title - ATG7 vs. ATG5: Distinct Autophagy Pathways Shaping TGF-β Signaling and Endothelial Function

Aman Singh, Bharatsinai Peddi, Kriti S. Bhatt, Hien Chi Nguyen, Krishna Kumar Singh

This study compares the roles of ATG5 and ATG7 in modulating TGF-β signaling and endothelial function, showing distinct effects on gene expression and cellular behavior.

PLoS ONE · Apr 30, 2026Peer-reviewedCell Biology

One-Pot NADH-Mediated Physiological Redox-Controlled Synthesis of Papain-Stabilized Copper Nanoclusters with Preserved Bioactivity for Efficient Drug Delivery

Aman Singh, Ananya Anand, Vanshika Vanshika, Anujit Balo, Dr. Farhan Ahmed, Mirzada Mohd Qounane, Koyel Banerjee-Ghosh, Ritaban Halder, Shirsendu Ghosh

This paper develops a one-pot, physiologically compatible synthesis of papain-stabilized copper nanoclusters using NADH as a reducing agent, showing enhanced helical stability and effective drug delivery with reduced IC50 in cancer cells.

bioRxiv · Apr 23, 2026 · PreprintBioengineering

The effect of fatty acid binding protein-3 exposure on endothelial transcriptomics

Hien Chi Nguyen, Aman Singh, Christina A. Castellani, Mohammad Qadura, Krishna Kumar Singh

This study examines how exposure to recombinant FABP3 affects endothelial cell transcriptomics, identifying key genes and pathways involved in immune response and angiogenesis.

DNA · Jan 8, 2026Peer-reviewedBiochemistry

Chloroquine Up-regulates Expression of SARS-CoV-2 receptor Angiotensin Converting Enzyme-2 in Endothelial Cells

Hien Chi Nguyen, Shuhan Bu, Y. Lynn Wang, Aman Singh, Krishna Kumar Singh

This study shows chloroquine increases ACE2 expression in endothelial cells, potentially worsening SARS-CoV-2 infection in patients with cardiovascular or kidney diseases.

bioRxiv · May 10, 2024 · PreprintCell Biology