Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response
Jiayi Fan, Nalini Dhingra, Tammy Yang, Vicki Yang, Xiaolan Zhao
This study investigates how Srs2 helicase interacts with PCNA and undergoes sumoylation to antagonize RPA and regulate the DNA damage checkpoint in yeast.
bioRxiv · Mar 28, 2024 · PreprintMolecular Biology