Author

Jiayi Fan

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-4317-8330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:software / tool· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Xiaolan ZhaoiD· 2 shared Aaron ScheiniD· 1 shared Alex B. CostaiD· 1 shared Anissia Ait SaadaiD· 1 shared Data Science Teamlab· 1 shared James Strong· 1 shared Jeffrey F. QuinniD· 1 shared John C. HoodiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Xiaolan ZhaoORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 1, 2026

Decoding Multicellular Communication Motifs from Spatial Transcriptomics with ALARMIST

Jiayi Fan, John C. Hood, James Strong…·Wesley Tansey

ALARMIST identifies multicellular communication motifs in spatial transcriptomics data, revealing microenvironmental drivers of tumor progression in lung and brain cancers.

DOI 10.64898/2026.05.21.726986

humanspatial transcriptomics

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Molecular BiologybioRxivPreprintMay 1, 2026

Replication fork remodeling proteins, Smc5/6 and Rtt107, promote palindrome-mediated genome instability

Alex B. Costa, Anissia Ait Saada, Thy Pham…·Kirill S. Lobachev

The paper identifies a pathway involving Smc5/6 and Rtt107 that promotes palindrome-mediated genome instability through cruciform formation and cleavage.

DOI 10.64898/2026.04.29.721645

humanexperimental assay

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Molecular BiologybioRxivPreprintMar 28, 2024

Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response

Jiayi Fan, Nalini Dhingra, Tammy Yang…·Xiaolan Zhao

This study investigates how Srs2 helicase interacts with PCNA and undergoes sumoylation to antagonize RPA and regulate the DNA damage checkpoint in yeast.

DOI 10.1101/2024.03.28.587206

yeaststatistical model

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