NeurosciencebioRxivPreprint
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models
R Chin, Rishi Rakhit, Dara Ditsworth…·Nicholas T. Hertz
This study identifies MTK458, a PINK1 activator, which reduces α-synuclein pathology and pUb levels in Parkinson's disease models and correlates plasma pUb with disease progression.