Author

Nicholas T. Hertz

Mitokinin (United States)ORCID 0000-0002-6527-6898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron D. GitleriD· 1 shared Akash ModyiD· 1 shared Alban OrdureauiD· 1 shared Alex Laishu· 1 shared Amy LiiD· 1 shared Ana JovičićiD· 1 shared Andrea EastesiD· 1 shared C. Kimberly TsuiiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Aaron D. GitlerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models

R Chin, Rishi Rakhit, Dara Ditsworth, Chengzhong Wang, Johan Bartholoméüs, Song Liu, Akash Mody, Alex Laishu, Andrea Eastes, Chao Tai, Roy Y. Kim, Jessica Li, Steven Hansberry, Saurabh Khasnavis, Victoria A. Rafalski, , Nicholas T. Hertz

This study identifies MTK458, a PINK1 activator, which reduces α-synuclein pathology and pUb levels in Parkinson's disease models and correlates plasma pUb with disease progression.

bioRxiv · Feb 14, 2023 · PreprintNeuroscience

CRISPR-Cas9 Screens In Human Cells And Primary Neurons Identify Modifiers Of C9orf72 Dipeptide Repeat Protein Toxicity

Nicholas J. Kramer, Michael Seamus Haney, David W. Morgens, Ana Jovičić, Julien Couthouis, Amy Li, James A. Ousey, Rosanna K. Ma, Gregor Bieri, C. Kimberly Tsui, Yingxiao Shi, Nicholas T. Hertz, Marc Tessier‐Lavigne, Justin K. Ichida, Michael Cory Bassik, Aaron D. Gitler

Genome-wide CRISPR-Cas9 screens in human cells reveal mechanisms and targets for ALS-associated C9orf72 dipeptide repeat protein toxicity.

Nature Genetics · Feb 28, 2018Peer-reviewedGenetics