Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors
K C Rajan, Nehal R Patel, Abbigail N. Thurmon, Belle L. Kantor, Maryann G Lorino, Alina S. Tiemroth, Vivianne E. Morrison, Mauren Akumuo, Anoushka Shenoy, Xabier Blanco-Fernandez, Victoria Baccini, Most Ayesha Siddika, Cong Gu, Stryder M. Meadows, Maria José Galazo
This study shows that loss of Zmiz1 in mice causes brain abnormalities and autistic-like behaviors, with molecular changes affecting neurogenesis and synaptic signaling.
Biological Psychiatry · Feb 1, 2026Peer-reviewedNeuroscience