Label-free Machine Learning Prediction of Chemotherapy on Tumor Spheroids using a Microfluidics Droplet Platform
Caroline Parent, Hasti Honari, Tiziana Tocci, Franck Simon, Sakina Zaïdi, Audric Jan, Vivian Aubert, Olivier Delattre, Hervé Isambert, Claire Wilhelm, Jean‐Louis Viovy
This paper develops a label-free platform combining microfluidics, morphological analysis, and machine learning to predict chemotherapy effects on tumor spheroids, showing robust performance across cell lines and patient-derived samples.
Small Science · Jul 16, 2025Peer-reviewedBioengineering