Author

W. A. Beenker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

J. den Hertog· 3 shared H. Clevers· 2 shared J. Hoeksma· 2 shared C. Pleguezuelos-Manzano· 1 shared G. D. Amatngalim· 1 shared G. J. F. van Son· 1 shared H. Beghtel· 1 shared J. M. Beekman· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

J. den Hertog

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Establishment and characterization of a new Pseudomonas aeruginosa infection model using 2D airway organoids and dual RNA sequencing

C. Pleguezuelos-Manzano, W. A. Beenker, G. J. F. van Son, H. Beghtel, G. D. Amatngalim, J. M. Beekman, H. Clevers, J. den Hertog

This study establishes a Pseudomonas aeruginosa infection model using 2D airway organoids and dual RNA sequencing to investigate host-bacterial interactions and quorum sensing effects.

bioRxiv · Mar 11, 2023 · PreprintMicrobiology

Paecilomycone inhibits quorum sensing in Gram-negative bacteria

W. A. Beenker, J. Hoeksma, M. Marie Bannier-Helaouët, H. Clevers, J. den Hertog

This paper identifies paecilomycone as a quorum sensing inhibitor in Pseudomonas aeruginosa, reducing virulence factors and biofilm formation with low eukaryotic toxicity.

bioRxiv · Sep 12, 2022Microbiology

Harzianic Acid has multi-target antimicrobial activity against Gram-Positive Bacteria

X. Ouyang, J. Hoeksma, W. A. Beenker, S. van der Beek, J. den Hertog

This study identifies harzianic acid as a multi-target antimicrobial compound effective against Gram-positive bacteria, with resistance linked to specific gene mutations.

bioRxiv · Dec 3, 2021 · PreprintMicrobiology