W. A. Cresko

Single Cell Sequencing Provides Clues about the Developmental Genetic Basis of Evolutionary Adaptations in Syngnathid Fishes

The paper uses single-cell RNA sequencing to analyze developmental genetic changes in Gulf pipefish embryos, identifying cell types and gene networks associated with evolutionary traits like toothlessness and dermal armor.

Host genomic variation shapes gut microbiome diversity in threespine stickleback fish

This study shows that host genetic variation influences gut microbiome diversity in threespine stickleback fish using a common garden experiment and genome-wide analysis.

Candidate Genes Underlying Wolbachia-Associated Plastic Recombination Revealed by Ovarian Transcriptomics of D. melanogaster

This study identifies candidate genes associated with Wolbachia-induced plastic recombination in D. melanogaster using ovarian transcriptomics.

A few stickleback suffice for the transport of alleles to new lakes

This study uses simulations to show that gene flow and migration-selection balance maintain adaptive alleles in marine stickleback populations, which are then used by freshwater populations for adaptation.

Genetic divergence outpaces phenotypic divergence among threespine stickleback populations in old freshwater habitats

The paper compares genetic and phenotypic divergence in threespine stickleback populations from Oregon and Alaska, finding greater genetic divergence in Oregon and unexpected affinities between oceanic and inland freshwater populations.

Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei

This study investigates the genetic architecture of heat and oxidative stress resistance in C. remanei, finding polygenic and largely independent genetic bases for these traits.

Highly reproducible 16S sequencing facilitates measurement of host genetic influences on the stickleback gut microbiome

The paper evaluates how tissue preparation and DNA isolation affect 16S sequencing of stickleback gut microbiomes, finding minor protocol effects compared to host genetic influences.

Environmental and evolutionary drivers of the modular gene regulatory network underlying phenotypic plasticity for stress resistance in the nematode Caenorhabditis remanei

The paper compares transcriptional responses to heat stress in four Caenorhabditis remanei populations, identifying plastic and evolutionary modules in gene regulatory networks.

Ancient genomic variation underlies repeated ecological adaptation in young stickleback populations

The paper identifies ancient genomic variation underlying repeated ecological adaptation in stickleback populations, showing that standing genetic variation from geological timescales drives rapid local adaptation.

Sweeping genomic remodeling through repeated selection of alternatively adapted haplotypes occurs in the first decades after marine stickleback colonize new freshwater ponds

This study shows that genomic remodeling through repeated selection of adapted haplotypes occurs rapidly in newly colonized freshwater ponds by marine stickleback fish.