Author

W. D. Ton

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Cell Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Beauchamp-Perez· 1 shared H. Xiong· 1 shared K. Zhang· 1 shared L. G. Lammers· 1 shared N. T. Flint· 1 shared P. Chai· 1 shared S. M. Markus· 1 shared Y. Wang· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

C. Beauchamp-Perez

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1 paper

Recent·Most cited

Microtubule binding-induced allostery promotes LIS1 dissociation from dynein prior to cargo transport

W. D. Ton, Y. Wang, P. Chai, C. Beauchamp-Perez, N. T. Flint, L. G. Lammers, H. Xiong, K. Zhang, S. M. Markus

The paper investigates how microtubule binding affects LIS1 dissociation from dynein, showing that MT-bound dynein has low LIS1 affinity while MT-unbound dynein binds LIS1 strongly.

bioRxiv · Nov 8, 2022 · PreprintCell Biology